Endocrine Abstracts

Subclinical Cushing’s syndrome (SCs) is used to refer to an adrenal incidentaloma with subtle autonomous cortisol secretion and without typical signs and symptoms of hypercortisolism. Diagnostic criteria are uncertain and arbitrary. In this study we aimed to investigate the power of adenoma size as an independent predictor of SCs.Dokuz Eylul University Adrenal Tumours Study Group database includes 596 patients by January 2016. Briefly, there are 332...

Introduction: Natural history of adrenal incidentalomas has not been totally understood. Current data from subjects with adrenal incidentalomas demonstrated an increased rate of metabolic disturbances and cardiovascular risk. It has been shown that subjects with subclinical cortisol excess were more susceptible to diabetes, hypertension, and obesity. However, there is no data regarding prospective cardiovascular risk evaluation in subjects with subclinical Cushing’s syndr...

Aim: Colonic polyps and thyroid nodules are common diseases and frequency increases with age. In the literature, there is no study investigating the relationship between colonic polyps and thyroid nodules. Therefore, this study was designed to investigate thyroid nodule frequency in patients who have colonic polyps.Material and methods: Sixty-six patients with colonic polyps and 146 patients without colonic polyps enrolled in the study. Age and sex match...

Introduction: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit and it can be seen on postadolescence period. Several studies show that adrenal and pituitary hormones have an important role in the pathogenesis. The studies which show the isotretinoin treatment takes effect on hormones are phenomenal in the literature. The aim of our study is to identify a hormonal alteration in the etiopathogenesis of acne vulgaris and to observe whether there is an alt...

A male patient aged 63 years old was admitted to the emergency department with the complaints of polydipsia, polyurea and dizziness. He had hypertension which was on a calcium channel blocker and his hypertension was in control. His plasma glucose was measured as 564 mg/dl and hospitalized due to his new onset diabetes. His family history showed that, his mother, uncle, aunt and all six brothers were diagnosed as diabetes mellitus. His uncle, aunt and aunts children were using...

Thyroid disorders and polycystic ovary syndrome (PCOS) are two of the most common endocrine disorders in general population. Autoimmune thyroid diseases are common autoimmune disorders that affect about 5% to 20% of women in childbearing age. In this study, we evaluate the comorbidity rate of euthyroid Hashimoto’s Thyroiditis (HT) in PCOS patients and possible influence of thyroid autoantibodies on clinical and laboratory findings of PCOS. This study includes 285 PCOS pat...

Background: Hyponatraemia is the most common electrolyte abnormality in hospitalised patients. It is an independent risk factor for mortality and is associated with increased length of hospital stay.Method: The objective of audit was to review practice of investigations and management of hyponatraemia in adults at Bedford hospital in line with evidence based guidelines including European Society of Endocrinology 2014 clinical practice guidance. An observ...

Objective: By the definition of vitamin D receptors in many tissues, many functions of vitamin D other than calcium homeostasis and bone metabolism were shown. A role for vitamin D is suggested in the pathogenesis of Graves disease because of the effects of vitamin D on the immune system. In our study the role of vitamin D deficiency in the activation of Graves disease, development of autoimmune thyroid disease and the relationship between vitamin D and inflammatory markers we...

Introduction: Thyroid ophthalmopathy occurs generally due to Graves’ disease. Only a few cases were reported about ophthalmopathy in the years following a thyroidectomy and RAI therapy or metastatic papillary thyroid cancer.Case: A forty-six-year-old female patient was operated on for the fine needle aspiration biopsy (FNAB) result of a suspicious follicular neoplasia. A pathology examination showed a papillary microcarcinoma and Hashimoto thyroidit...

Patients with Addison’s or adrenal insufficiency require regular steroid replacement usually in the form of oral hydrocortisone. Standard advice is given on how to deal with intercurrent illness and special situations such as surgery. Organisations such as the Addison’s disease self-help group provide authoritative guidelines for patients. Several of our patients with adrenal insufficiency have asked how their steroid replacement treatment should be adjusted for expe...